nsg mouse Search Results


90
Jackson Laboratory immunodeficient mouse strains nrg mice #007799
Immunodeficient Mouse Strains Nrg Mice #007799, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Jackson Laboratory nsg mouse strain
Nsg Mouse Strain, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Johns Hopkins HealthCare ll/2 metastasis in nsg mouse model
(A) In vitro transfection efficiencies of nanoparticles (W1–W8, see Table 1) in PC3 cancer cell line (dose = 0.6 μg gWiz-Luc plasmid/104 cells); (B) In vivo transfection efficiency in the lung in <t>healthy</t> <t>BALB/c</t> mice at 12 h post i.v. injection of nanoparticles (W1–W8, see Table 1) containing 40 μg gWiz-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (C) In vivo transfection efficiency in the lung of an LL/2 metastasis model in the <t>NSG</t> mice at 48 h post injection of nanoparticles (P1-P8, see Table 1) containing 40 μg PEG-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (D) Whole-body biodistributions in BALB/c mice at 1 h post injection of nanoparticles (W1, W2, W6, W8) containing 40 μg 3H-labeled gWiz-Luc plasmid per mouse. Labels: H: heart, K: kidneys, S: stomach, SI: small intestine; (E) Biodistributions to the lung of mice shown in (D); For statistical analysis, n.s. denotes no statistical significance with p > 0.05, *p < 0.05, **p < 0.01, and ***p < 0.001 from one-way or two-way ANOVA and multiple comparisons.
Ll/2 Metastasis In Nsg Mouse Model, supplied by Johns Hopkins HealthCare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Jackson Laboratory nsg mouse breeding pairs
(A) In vitro transfection efficiencies of nanoparticles (W1–W8, see Table 1) in PC3 cancer cell line (dose = 0.6 μg gWiz-Luc plasmid/104 cells); (B) In vivo transfection efficiency in the lung in <t>healthy</t> <t>BALB/c</t> mice at 12 h post i.v. injection of nanoparticles (W1–W8, see Table 1) containing 40 μg gWiz-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (C) In vivo transfection efficiency in the lung of an LL/2 metastasis model in the <t>NSG</t> mice at 48 h post injection of nanoparticles (P1-P8, see Table 1) containing 40 μg PEG-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (D) Whole-body biodistributions in BALB/c mice at 1 h post injection of nanoparticles (W1, W2, W6, W8) containing 40 μg 3H-labeled gWiz-Luc plasmid per mouse. Labels: H: heart, K: kidneys, S: stomach, SI: small intestine; (E) Biodistributions to the lung of mice shown in (D); For statistical analysis, n.s. denotes no statistical significance with p > 0.05, *p < 0.05, **p < 0.01, and ***p < 0.001 from one-way or two-way ANOVA and multiple comparisons.
Nsg Mouse Breeding Pairs, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Jackson Laboratory nsg-il-6 mouse
(A) In vitro transfection efficiencies of nanoparticles (W1–W8, see Table 1) in PC3 cancer cell line (dose = 0.6 μg gWiz-Luc plasmid/104 cells); (B) In vivo transfection efficiency in the lung in <t>healthy</t> <t>BALB/c</t> mice at 12 h post i.v. injection of nanoparticles (W1–W8, see Table 1) containing 40 μg gWiz-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (C) In vivo transfection efficiency in the lung of an LL/2 metastasis model in the <t>NSG</t> mice at 48 h post injection of nanoparticles (P1-P8, see Table 1) containing 40 μg PEG-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (D) Whole-body biodistributions in BALB/c mice at 1 h post injection of nanoparticles (W1, W2, W6, W8) containing 40 μg 3H-labeled gWiz-Luc plasmid per mouse. Labels: H: heart, K: kidneys, S: stomach, SI: small intestine; (E) Biodistributions to the lung of mice shown in (D); For statistical analysis, n.s. denotes no statistical significance with p > 0.05, *p < 0.05, **p < 0.01, and ***p < 0.001 from one-way or two-way ANOVA and multiple comparisons.
Nsg Il 6 Mouse, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Jackson Laboratory hprt-null nsg mice mouse #012480
(A) In vitro transfection efficiencies of nanoparticles (W1–W8, see Table 1) in PC3 cancer cell line (dose = 0.6 μg gWiz-Luc plasmid/104 cells); (B) In vivo transfection efficiency in the lung in <t>healthy</t> <t>BALB/c</t> mice at 12 h post i.v. injection of nanoparticles (W1–W8, see Table 1) containing 40 μg gWiz-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (C) In vivo transfection efficiency in the lung of an LL/2 metastasis model in the <t>NSG</t> mice at 48 h post injection of nanoparticles (P1-P8, see Table 1) containing 40 μg PEG-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (D) Whole-body biodistributions in BALB/c mice at 1 h post injection of nanoparticles (W1, W2, W6, W8) containing 40 μg 3H-labeled gWiz-Luc plasmid per mouse. Labels: H: heart, K: kidneys, S: stomach, SI: small intestine; (E) Biodistributions to the lung of mice shown in (D); For statistical analysis, n.s. denotes no statistical significance with p > 0.05, *p < 0.05, **p < 0.01, and ***p < 0.001 from one-way or two-way ANOVA and multiple comparisons.
Hprt Null Nsg Mice Mouse #012480, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Charles River Laboratories nsg mouse/human aml nod-scid common γ-chain knockout mice (nsg
(A) In vitro transfection efficiencies of nanoparticles (W1–W8, see Table 1) in PC3 cancer cell line (dose = 0.6 μg gWiz-Luc plasmid/104 cells); (B) In vivo transfection efficiency in the lung in <t>healthy</t> <t>BALB/c</t> mice at 12 h post i.v. injection of nanoparticles (W1–W8, see Table 1) containing 40 μg gWiz-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (C) In vivo transfection efficiency in the lung of an LL/2 metastasis model in the <t>NSG</t> mice at 48 h post injection of nanoparticles (P1-P8, see Table 1) containing 40 μg PEG-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (D) Whole-body biodistributions in BALB/c mice at 1 h post injection of nanoparticles (W1, W2, W6, W8) containing 40 μg 3H-labeled gWiz-Luc plasmid per mouse. Labels: H: heart, K: kidneys, S: stomach, SI: small intestine; (E) Biodistributions to the lung of mice shown in (D); For statistical analysis, n.s. denotes no statistical significance with p > 0.05, *p < 0.05, **p < 0.01, and ***p < 0.001 from one-way or two-way ANOVA and multiple comparisons.
Nsg Mouse/Human Aml Nod Scid Common γ Chain Knockout Mice (Nsg, supplied by Charles River Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Brehm GmbH nsg- b2m nu11 ( ia ie ) null mouse strains
Mouse strains that support high levels of engraftment with human hematopoietic and immune cells
Nsg B2m Nu11 ( Ia Ie ) Null Mouse Strains, supplied by Brehm GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Charles River Laboratories mouse strain/line name nsg
Mouse strains that support high levels of engraftment with human hematopoietic and immune cells
Mouse Strain/Line Name Nsg, supplied by Charles River Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Mispro Biotech Services mouse (nsg, skin)
Mouse strains that support high levels of engraftment with human hematopoietic and immune cells
Mouse (Nsg, Skin), supplied by Mispro Biotech Services, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Jackson Laboratory mouse: nsg-hla:a*02 transgenic
Mouse strains that support high levels of engraftment with human hematopoietic and immune cells
Mouse: Nsg Hla:A*02 Transgenic, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Jackson Laboratory immune-deficient non-obese diabetic scid gamma (nsg) mouse breeders
Mouse strains that support high levels of engraftment with human hematopoietic and immune cells
Immune Deficient Non Obese Diabetic Scid Gamma (Nsg) Mouse Breeders, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


(A) In vitro transfection efficiencies of nanoparticles (W1–W8, see Table 1) in PC3 cancer cell line (dose = 0.6 μg gWiz-Luc plasmid/104 cells); (B) In vivo transfection efficiency in the lung in healthy BALB/c mice at 12 h post i.v. injection of nanoparticles (W1–W8, see Table 1) containing 40 μg gWiz-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (C) In vivo transfection efficiency in the lung of an LL/2 metastasis model in the NSG mice at 48 h post injection of nanoparticles (P1-P8, see Table 1) containing 40 μg PEG-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (D) Whole-body biodistributions in BALB/c mice at 1 h post injection of nanoparticles (W1, W2, W6, W8) containing 40 μg 3H-labeled gWiz-Luc plasmid per mouse. Labels: H: heart, K: kidneys, S: stomach, SI: small intestine; (E) Biodistributions to the lung of mice shown in (D); For statistical analysis, n.s. denotes no statistical significance with p > 0.05, *p < 0.05, **p < 0.01, and ***p < 0.001 from one-way or two-way ANOVA and multiple comparisons.

Journal: ACS nano

Article Title: Kinetic Control in Assembly of Plasmid DNA/Polycation Complex Nanoparticles

doi: 10.1021/acsnano.9b03334

Figure Lengend Snippet: (A) In vitro transfection efficiencies of nanoparticles (W1–W8, see Table 1) in PC3 cancer cell line (dose = 0.6 μg gWiz-Luc plasmid/104 cells); (B) In vivo transfection efficiency in the lung in healthy BALB/c mice at 12 h post i.v. injection of nanoparticles (W1–W8, see Table 1) containing 40 μg gWiz-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (C) In vivo transfection efficiency in the lung of an LL/2 metastasis model in the NSG mice at 48 h post injection of nanoparticles (P1-P8, see Table 1) containing 40 μg PEG-Luc plasmid per mouse (left) and representative IVIS images of groups with significant differences in transgene expression (right); (D) Whole-body biodistributions in BALB/c mice at 1 h post injection of nanoparticles (W1, W2, W6, W8) containing 40 μg 3H-labeled gWiz-Luc plasmid per mouse. Labels: H: heart, K: kidneys, S: stomach, SI: small intestine; (E) Biodistributions to the lung of mice shown in (D); For statistical analysis, n.s. denotes no statistical significance with p > 0.05, *p < 0.05, **p < 0.01, and ***p < 0.001 from one-way or two-way ANOVA and multiple comparisons.

Article Snippet: Preliminary tests revealed that the transgene expression level (luciferase concentration in healthy lung tissues or tumor cells in the lung) peaks at around 12 and 48–72 h post injection for healthy BALB/c mouse model (Jackson Laboratory, US) and LL/2 metastasis in NSG mouse model (Johns Hopkins University Animal Core), respectively.

Techniques: In Vitro, Transfection, Plasmid Preparation, In Vivo, Injection, Expressing, Labeling

Mouse strains that support high levels of engraftment with human hematopoietic and immune cells

Journal: Mammalian genome : official journal of the International Mammalian Genome Society

Article Title: Humanized Mouse Models of Immunological Diseases and Precision Medicine

doi: 10.1007/s00335-019-09796-2

Figure Lengend Snippet: Mouse strains that support high levels of engraftment with human hematopoietic and immune cells

Article Snippet: Our laboratories developed two NSG strains deficient in murine MHC class I and class II, the NOD.Cg- B2m tm1Unc Prkdc scid H2 dlAb1Ea Il2rg tm1Wjl/Sz /SzJ, abbreviated as NSG- B2M nu11 ( IA IE ) null and NOD.Cg- Prkdc scid H2Ab1 em1Mwv H2K1 tmiBpe H2D1 tmiBpe Il2rg tm1Wjl/Sz /SzJ , abbreviated as,NSG-( K b D b ) null ( IA null ) mouse strains ( Brehm et al. 2018 ).

Techniques: Transgenic Assay, Expressing, Control, Membrane, Knock-In, Irradiation, Injection, Mutagenesis, Knock-Out, Activity Assay, Sequencing